Desquiciada means 'unhinged' or 'deranged'. It's a fantastic descriptive word that comes from the verb desquiciar, which literally means to knock a door off its hinges!
In the song, Shakira uses this word to paint a picture of how love has made her lose her mind, describing herself as completely out of control. This powerful imagery of being 'unhinged' perfectly captures the chaotic and maddening side of a passionate romance.
Colombian superstar Shakira turns the dizzying mess of an uncontrollable crush into pure pop energy in "Ciega, Sordomuda". Instead of romanticizing love, she describes it as a complete loss of dignity and common sense. The moment her crush walks in, her logic and plan fly out the window: "Se me acaba el argumento / Y la metodología / Cada vez que se aparece / Frente a mí tu anatomía" ("I run out of arguments and methodology every time your anatomy appears in front of me"). She says this love has no guts—literally "le faltan pantalones" ("it lacks pants", meaning courage or decency)—and it leaves her stumbling around, picking fights with the entire world while obsessing over him day and night.
Her famous chorus unleashes a hilarious, rapid-fire rant of self-insults. Love makes her feel "bruta, ciega, sordomuda, torpe, traste, testaruda" ("clueless, blind, deaf-mute, clumsy, useless junk, stubborn"). Later, she rattles off an even longer list of chaotic states, calling herself "ojerosa, flaca, fea, desgreñada" ("sleep-deprived with dark circles, skinny, ugly, disheveled") and "completamente descontrolada" ("completely out of control"). She describes her own brain turning into a messy nest ("un nido") where only he gets free rent. It is frantic, self-deprecating, and wildly fun to sing along to as you build your vocabulary!