Loquera is a fantastic slang term for 'craziness' or a 'wild phase'. It's derived from the word loco (crazy) and describes a whole period or lifestyle of wild, chaotic behavior.
In the song, the artist sings, "me hice adicto a andar en esta loquera" (I got addicted to living in this craziness). He uses this powerful word to describe the wild lifestyle of money and partying he fell into after the relationship went sour. It’s a much more expressive and specific term than the standard word for madness, locura.
In "DOS DÍAS", Mexican artist Tito Double P teams up with Peso Pluma to air out the messy aftermath of an argument with a lover. The story starts with a petty grudge: she has been furious for forty-eight hours straight, giving him the silent treatment ("Dos días enojada, dos días que no me hablas" [Two days angry, two days you don't talk to me]). Instead of sitting at home feeling sad, the narrator heads out with his crew ("los panas" [the homies]), mixing drinks ("tragos pa' la panza" [drinks for the belly]) and drugs ("ese periquito" [that little parakeet, Mexican slang for cocaine]). All the plans they had together instantly went down the drain ("se nos fue a la chingada" [went straight to hell]). It is blunt, petty, and chaotic from the very first verse.
The chorus reveals the real damage, where he blames her for the wild, out-of-control lifestyle he fell into. He admits he warned her that being on his own turns him into a disaster ("yo era un cagadero" [I was a total mess]). Now he obsesses over stacks of cash ("pacas" [cash bundles]) and partying hard ("esta loquera" [this madness]), but brags that none of the superficial attention from other women satisfies him ("ni uno me llena" [not one fulfills me]). Between awkward drive-bys waving at her mom and reminiscing about hooking up in her living room, Tito Double P delivers a brutally honest look at reckless heartbreak where partying is just an excuse to cope with being ignored.